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GC-MS analysis of apolar extract of Astragalus sibthorpianus

Year 2019, Volume: 3 Issue: 1, 32 - 37, 24.06.2019

Nevin Arıkan Ölmez , Gürcan Güleryüz Ömer Koz

https://doi.org/10.38088/jise.570007

Abstract

Astragalus species are widely
distributed in Turkey. There are 445 species in the Flora of Turkey. Plenty of
species of Astragalus are used in
traditional medicine in many countries such as European Countries, Turkey,
China, India etc. They are used for treatment of diabetes, nephritis,
leukaemia, and uterine cancer. In addition, they are used as an antiperspirant,
diuretic, and tonic drug. Astragalus sibthorpianus is
endemic to Uludağ mountain in Turkey. In this study for the first time, the
chemical composition of n-hexane extract of plant material was investigated
using GC-MS. The whole plant material was dried and powdered and macerated with
MeOH at room temperature. The concentrated MeOH layer was extracted with
n-hexane for the apolar constituents. The crude n-hexane extract was
derivatized and identification of each component was exhibited by Wiley library
data search.

Keywords

Astragalus sibthorpianus GC-MS Hexane extract

Supporting Institution

Uludag University

Project Number

KUAP(F)-2013-85

Thanks

The authors acknowledge to Uludag University for financial support.

References

  • [1] Davis, P.H., (1970). Flora of Turkey and East Aegean Islands, vol. 3., pp. 49–254, Edinburgh University Press, Edinburgh.
  • [2] Aytaç, Z., (2000). Astragalus L.-In: Güner, A., Ozhatay N., Ekim, T., Başar, K. H. C. (eds.), Flora of Turkey and the East Aegean Islands, Edinburgh University Press. Edinburgh.
  • [3] Tang W., Eisenbrand G., (1992) Chinese Drugs of Plant Origin, Springer-Verlag. Berlin, 191-197
  • [4] Lev, E., (2002). Reconstructed materia medica of the Medieval and Ottoman al-Sham, Journal of Ethnopharmacology, 80, 167-179.
  • [5] Cakilcioglu, U., Turkoglu, I., (2010). An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey), Journal of Ethnopharmacology, 132, 165–175.
  • [6] Uphof, J. C. Th., (1968). Dictionary of economic plants, Verlag von J. Cramer Lehre, 2. edn., 591 pp
  • [7] Ralphs, M. H., Panter, K. E., James, L. F., (1990). Feed preferences and habituation of sheep poisoned by locoweed, Journal of Animal Science, 68, 1354-1362
  • [8] James, L. F., Panter, K. E., Nielsen, D. B., Molyneux, R. J., (1992). The effect of natural toxins on reproduction in livestock, Journal of Animal Science, 70, 1573-1579.
  • [9] Rios, L. J., Waterman, P.G., (1997). A review of the pharmacology and toxicology of Astragalus. Phytotherapy Research. 11, 411–418.
  • [10] Bedir, E., Pugh, N. P., Calis, I., Pasco, D. A., Khan, I. A. (2000). Immunostimulatory effects of cycloartane-type triterpene glycosides from Astragalus species, Biological and Pharmaceutical Bulletin. 23, 834-837.
  • [11] Li, X. Y., (2000). Immuno-modulating components from Chinese medicines, Pharmaceutical Biology, 38, 33–40.
  • [12] International Olive Oil Council (2001). Method of Analysis. International Olive Oil Council COI/T. 20/ Doc. no. 24.
  • [13] Paquat C, Hautfenne A (1987). Standard methods for the analysis of oils, fats, and derivatives, International Union of Pure and Applied Chemistry. Blackwell Scientific Publications, Oxford.
  • [14] Huertas, E. L., Baro, L., Carrero, J. J., Fonolla J., Jimenez, J., Boza, J. J., (2003). n-3 Fatty Acids: Health Effects and Opportunities to Increase Intake, AGRO Food Industry Hitech, 18-21
  • [15] Innis, S. M., (2000). Essential fatty acids in infant nutrition: lessons and limitations from animal studies in relation to studies on infant fatty acid requirements, The American Journal of Clinical Nutrition, 71, 238-244.
  • [16] Connor, W. E., (2000). Importance of n−3 fatty acids in health and disease, The American Journal of Clinical Nutrition, 71, 171-175.
  • [17] Eynard, A. R. (2003). Potential of essential fatty acids as natural therapeutic products for human tumours, Nutrition, 19, 386-388.
  • [18] Kang J. X., Leaf A., (2000). Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids, The American Journal of Clinical Nutrition, 71, 202–207.
  • [19] Konukoglu, D., (2008). Properties, functions of omega-3 and omega-6 fatty acids and relationship between essential fatty acids and cardiovascular diseases, Türkiye Aile Hekimliği Dergisi, 12 (3), 121-129.
  • [20] Bağcı E., Bruehl L., Aitzetmuller K., Altan Y. (2003) A chemotaxonomic approach on the fatty acid and tocochromanol content of Cannabis sativa L. (Cannabaceae). Turkish Journal of Botany 27(2):141-147

Year 2019, Volume: 3 Issue: 1, 32 - 37, 24.06.2019

Nevin Arıkan Ölmez , Gürcan Güleryüz Ömer Koz

https://doi.org/10.38088/jise.570007

Abstract

Project Number

KUAP(F)-2013-85

References

  • [1] Davis, P.H., (1970). Flora of Turkey and East Aegean Islands, vol. 3., pp. 49–254, Edinburgh University Press, Edinburgh.
  • [2] Aytaç, Z., (2000). Astragalus L.-In: Güner, A., Ozhatay N., Ekim, T., Başar, K. H. C. (eds.), Flora of Turkey and the East Aegean Islands, Edinburgh University Press. Edinburgh.
  • [3] Tang W., Eisenbrand G., (1992) Chinese Drugs of Plant Origin, Springer-Verlag. Berlin, 191-197
  • [4] Lev, E., (2002). Reconstructed materia medica of the Medieval and Ottoman al-Sham, Journal of Ethnopharmacology, 80, 167-179.
  • [5] Cakilcioglu, U., Turkoglu, I., (2010). An ethnobotanical survey of medicinal plants in Sivrice (Elazığ-Turkey), Journal of Ethnopharmacology, 132, 165–175.
  • [6] Uphof, J. C. Th., (1968). Dictionary of economic plants, Verlag von J. Cramer Lehre, 2. edn., 591 pp
  • [7] Ralphs, M. H., Panter, K. E., James, L. F., (1990). Feed preferences and habituation of sheep poisoned by locoweed, Journal of Animal Science, 68, 1354-1362
  • [8] James, L. F., Panter, K. E., Nielsen, D. B., Molyneux, R. J., (1992). The effect of natural toxins on reproduction in livestock, Journal of Animal Science, 70, 1573-1579.
  • [9] Rios, L. J., Waterman, P.G., (1997). A review of the pharmacology and toxicology of Astragalus. Phytotherapy Research. 11, 411–418.
  • [10] Bedir, E., Pugh, N. P., Calis, I., Pasco, D. A., Khan, I. A. (2000). Immunostimulatory effects of cycloartane-type triterpene glycosides from Astragalus species, Biological and Pharmaceutical Bulletin. 23, 834-837.
  • [11] Li, X. Y., (2000). Immuno-modulating components from Chinese medicines, Pharmaceutical Biology, 38, 33–40.
  • [12] International Olive Oil Council (2001). Method of Analysis. International Olive Oil Council COI/T. 20/ Doc. no. 24.
  • [13] Paquat C, Hautfenne A (1987). Standard methods for the analysis of oils, fats, and derivatives, International Union of Pure and Applied Chemistry. Blackwell Scientific Publications, Oxford.
  • [14] Huertas, E. L., Baro, L., Carrero, J. J., Fonolla J., Jimenez, J., Boza, J. J., (2003). n-3 Fatty Acids: Health Effects and Opportunities to Increase Intake, AGRO Food Industry Hitech, 18-21
  • [15] Innis, S. M., (2000). Essential fatty acids in infant nutrition: lessons and limitations from animal studies in relation to studies on infant fatty acid requirements, The American Journal of Clinical Nutrition, 71, 238-244.
  • [16] Connor, W. E., (2000). Importance of n−3 fatty acids in health and disease, The American Journal of Clinical Nutrition, 71, 171-175.
  • [17] Eynard, A. R. (2003). Potential of essential fatty acids as natural therapeutic products for human tumours, Nutrition, 19, 386-388.
  • [18] Kang J. X., Leaf A., (2000). Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids, The American Journal of Clinical Nutrition, 71, 202–207.
  • [19] Konukoglu, D., (2008). Properties, functions of omega-3 and omega-6 fatty acids and relationship between essential fatty acids and cardiovascular diseases, Türkiye Aile Hekimliği Dergisi, 12 (3), 121-129.
  • [20] Bağcı E., Bruehl L., Aitzetmuller K., Altan Y. (2003) A chemotaxonomic approach on the fatty acid and tocochromanol content of Cannabis sativa L. (Cannabaceae). Turkish Journal of Botany 27(2):141-147
There are 20 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Research Articles
Authors

Nevin Arıkan Ölmez 0000-0002-0824-1162

Gürcan Güleryüz 0000-0001-5441-037X

Ömer Koz 0000-0002-2882-6811

Project Number KUAP(F)-2013-85
Publication Date June 24, 2019
Published in Issue Year 2019Volume: 3 Issue: 1

Cite

APA Arıkan Ölmez, N., Güleryüz, G., & Koz, Ö. (2019). GC-MS analysis of apolar extract of Astragalus sibthorpianus. Journal of Innovative Science and Engineering, 3(1), 32-37. https://doi.org/10.38088/jise.570007
AMA Arıkan Ölmez N, Güleryüz G, Koz Ö. GC-MS analysis of apolar extract of Astragalus sibthorpianus. JISE. June 2019;3(1):32-37. doi:10.38088/jise.570007
Chicago Arıkan Ölmez, Nevin, Gürcan Güleryüz, and Ömer Koz. “GC-MS Analysis of Apolar Extract of Astragalus Sibthorpianus”. Journal of Innovative Science and Engineering 3, no. 1 (June 2019): 32-37. https://doi.org/10.38088/jise.570007.
EndNote Arıkan Ölmez N, Güleryüz G, Koz Ö (June 1, 2019) GC-MS analysis of apolar extract of Astragalus sibthorpianus. Journal of Innovative Science and Engineering 3 1 32–37.
IEEE N. Arıkan Ölmez, G. Güleryüz, and Ö. Koz, “GC-MS analysis of apolar extract of Astragalus sibthorpianus”, JISE, vol. 3, no. 1, pp. 32–37, 2019, doi: 10.38088/jise.570007.
ISNAD Arıkan Ölmez, Nevin et al. “GC-MS Analysis of Apolar Extract of Astragalus Sibthorpianus”. Journal of Innovative Science and Engineering 3/1 (June 2019), 32-37. https://doi.org/10.38088/jise.570007.
JAMA Arıkan Ölmez N, Güleryüz G, Koz Ö. GC-MS analysis of apolar extract of Astragalus sibthorpianus. JISE. 2019;3:32–37.
MLA Arıkan Ölmez, Nevin et al. “GC-MS Analysis of Apolar Extract of Astragalus Sibthorpianus”. Journal of Innovative Science and Engineering, vol. 3, no. 1, 2019, pp. 32-37, doi:10.38088/jise.570007.
Vancouver Arıkan Ölmez N, Güleryüz G, Koz Ö. GC-MS analysis of apolar extract of Astragalus sibthorpianus. JISE. 2019;3(1):32-7.
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