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Yıl 2022, Cilt: 6 Sayı: 2, 142 - 146, 31.12.2022

Ramazan Erenler Esma Nur Geçer Büşra Moran Bozer

https://doi.org/10.32571/ijct.1187754

Öz

Kaynakça

  • 1. Topçu, G.; Erenler, R.; Çakmak, O.; Johansson, C. B.; Çelik, C.; Chai, H.-B.; Pezzuto, J. M. Phytochemistry 1999, 50 (7), 1195-1199.
  • 2. Elmastas, M.; Ozturk, L.; Gokce, I.; Erenler, R.; Aboul-Enein, H. Y. Anal. Lett. 2004, 37 (9), 1859-1869.
  • 3. Demirtas, I.; Erenler, R.; Elmastas, M.; Goktasoglu, A. Food Chem. 2013, 136 (1), 34-40.
  • 4. Erenler, R.; Yilmaz, S.; Aksit, H.; Sen, O.; Genc, N.; Elmastas, M.; Demirtas, I. Rec. Nat. Prod. 2014, 8 (1), 32-36.
  • 5. Kaya, G.; Karakaya, R.; Tilgel, E.; Sandikci, M.; Yucel, E.; Cicek, G.; Kayir, O.; Aksit, H.; Telci, I.; Guzel, A. J. New Results Sci. 2014, 7 (7), 1-6.
  • 6. Türkmen, N.; Öz, A.; Sönmez, A.; Erol, T.; Gülümser, D.; Yurdakul, B.; Kayır, Ö.; Elmastas, M.; Erenler, R. J. New Results Sci. 2014, 6 (6), 27-31.
  • 7. Saidi, A.; Hambaba, L.; Kucuk, B.; Cacan, E.; Erenler, R. Curr. Bioact. Compd. 2022, 18 (3), 72-83.
  • 8. Koysu, P.; Genc, N.; Elmastas, M.; Aksit, H.; Erenler, R. Nat. Prod. Res. 2019, 33 (24), 3592-3595.
  • 9. Erenler, R.; Telci, I.; Ulutas, M.; Demirtas, I.; Gul, F.; Elmastas, M.; Kayir, O. J. Food Biochem. 2015, 39 (5), 622-630.
  • 10. Dede, E.; Genc, N.; Elmastas, M.; Aksit, H.; Erenler, R. Nat. Prod. J. 2019, 9 (3), 238-243.
  • 11. Erenler, R.; Nusret, G.; Elmastaş, M.; Eminağaoğlu, Ö. Turk. J. Biodiv. 2019, 2 (1), 13-17.
  • 12. Nusret, G.; Elmastas, M.; Telci, I.; Erenler, R. Int. J. Chem. Technol. 2020, 4 (2), 179-184.
  • 13. Aydin, A.; Erenler, R.; Yılmaz, B.; Tekin, Ş. J. Turk. Chem. Soc., Sec A: Chem 2016, 3 (3), 217-228.
  • 14. Elmastas, M.; Erenler, R.; Isnac, B.; Aksit, H.; Sen, O.; Genc, N.; Demirtas, I. Nat. Prod. Res. 2016, 30 (3), 299-304.
  • 15. Gecer, E. N. J. Inorg. Organomet. Polym. Mater. 2021, 31 (11), 4402-4409.
  • 16. Gecer, E. N.; Erenler, R.; Temiz, C.; Genc, N.; Yildiz, I. Particul. Sci. Technol. 2021, 40 (1), 50-57.
  • 17. Genc, N. Particul. Sci. Technol. 2021, 39 (5), 562-568.
  • 18. Genc, N.; Yildiz, I.; Chaoui, R.; Erenler, R.; Temiz, C.; Elmastas, M. Inorg. Nano-Met. Chem. 2021, 51 (3), 411-419.
  • 19. Burlacu, E.; Tanase, C.; Coman, N.-A.; Berta, L. Molecules 2019, 24 (23), 4354.
  • 20. de Souza, T. A. J.; Souza, L. R. R.; Franchi, L. P. Ecotox. Environ. Safe. 2019, 171, 691-700.
  • 21. El-Seedi, H. R.; El-Shabasy, R. M.; Khalifa, S. A.; Saeed, A.; Shah, A.; Shah, R.; Iftikhar, F. J.; Abdel-Daim, M. M.; Omri, A.; Hajrahand, N. H. RSC Adv. 2019, 9 (42), 24539-24559.
  • 22. Faraz, A.; Faizan, M.; Sami, F.; Siddiqui, H.; Pichtel, J.; Hayat, S. IET Nanobiotech. 2019, 13 (4), 345-352.
  • 23. Ökten, S.; Çakmak, O.; Erenler, R.; Yüce, Ö.; Tekin, S. Turk. J. Chem. 2013, 37 (6), 896-908.
  • 24. G Ravelo, A.; Estévez-Braun, A.; Chávez-Orellana, H.; Pérez-Sacau, E.; Mesa-Siverio, D. Curr. Top. Med. Chem. 2004, 4 (2), 241-265.
  • 25. Erenler, R.; Meral, B.; Sen, O.; Elmastas, M.; Aydin, A.; Eminagaoglu, O.; Topcu, G. Pharm. Biol. 2017, 55 (1), 1646-1653.
  • 26. Elmastas, M.; Celik, S. M.; Genc, N.; Aksit, H.; Erenler, R.; Gulcin, İ. Int. J. Food Prop. 2018, 21 (1), 374-384.
  • 27. Erenler, R.; Demirtas, I.; Karan, T.; Gul, F.; Kayir, O.; Karakoc, O. C. Trends Phytochem. Res. 2018, 2 (2), 91-96.
  • 28. Karan, T.; Simsek, S.; Yildiz, I.; Erenler, R. Int. J. Sec. Metabol. 2018, 5 (2), 87-93.
  • 29. Erenler, R.; Sen, O.; Aksit, H.; Demirtas, I.; Yaglioglu, A. S.; Elmastas, M.; Telci, İ. J. Sci. Food Agr. 2016, 96 (3), 822-836.
  • 30. Erenler, R.; Dag, B. Inorg. Nano-Met. Chem. 2022, 52 (4), 485-492.
  • 31. Sahin Yaglioglu, A.; Akdulum, B.; Erenler, R.; Demirtas, I.; Telci, I.; Tekin, S. Med. Chem. Res. 2013, 22 (6), 2946-2953.
  • 32. Erenler, R.; Pabuccu, K.; Yaglioglu, A. S.; Demirtas, I.; Gul, F. Z. Naturforsch. C 2016, 71 (3-4), 87-92.
  • 33. Erenler, R.; Sen, O.; Yaglioglu, A. S.; Demirtas, I. Comb. Chem. High. T. Scr. 2016, 19 (1), 66-72.
  • 34. Erenler, R.; Sen, O.; Yildiz, I.; Aydın, A. Rec. Nat. Prod. 2016, 10 (6), 766-770.
  • 35. Karan, T.; Erenler, R.; Bozer, B. M. Z. Naturforsch. C 2022.
  • 36. Hu, W.; Kavanagh, J. J. Lancet Oncol. 2003, 4 (12), 721-729.

Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract

Yıl 2022, Cilt: 6 Sayı: 2, 142 - 146, 31.12.2022

Ramazan Erenler Esma Nur Geçer Büşra Moran Bozer

https://doi.org/10.32571/ijct.1187754

Öz

application. Anticancer activity of Origanum majorana extract and silver nanoparticles was investigated by MTT assay using human pancreatic adenocarcinoma cell lines (Capan-1), mouse normal fibroblast cell lines (L929), and human colon adenocarcinoma cell line (Caco-2). AgNPs@Om exhibited the excellent cytotoxic effect on Capan-1 cell lines with the cell viability of 29.17% and 25.70%, 22.49%, 21.16% at 1.0, 0.5, 0.25, 0.125 μg/mL respectively. However, the extract was determined to show moderate activity. A considerable fall in the viable cell number in Caco-2 cell lines was observed after the treatment of AgNPs@Om. The viable cells of Caco-2 cell lines were detected as 32.0% at 1.0 μg/mL with the treatment of nanoparticles. Yet, the viable Caco-2 cells were determined as 48.2% with the treatment of O. majorana extract. Both extract and nanoparticles had no impact on the viability of non-tumor cells (L929). Moreover, nanoparticles induced apoptosis. Consequently, AgNPs@Om may be a promising anticancer drug candidate.

Anahtar Kelimeler

Silver nanoparticles natural products Origanum majorana anticancer activity.

Kaynakça

  • 1. Topçu, G.; Erenler, R.; Çakmak, O.; Johansson, C. B.; Çelik, C.; Chai, H.-B.; Pezzuto, J. M. Phytochemistry 1999, 50 (7), 1195-1199.
  • 2. Elmastas, M.; Ozturk, L.; Gokce, I.; Erenler, R.; Aboul-Enein, H. Y. Anal. Lett. 2004, 37 (9), 1859-1869.
  • 3. Demirtas, I.; Erenler, R.; Elmastas, M.; Goktasoglu, A. Food Chem. 2013, 136 (1), 34-40.
  • 4. Erenler, R.; Yilmaz, S.; Aksit, H.; Sen, O.; Genc, N.; Elmastas, M.; Demirtas, I. Rec. Nat. Prod. 2014, 8 (1), 32-36.
  • 5. Kaya, G.; Karakaya, R.; Tilgel, E.; Sandikci, M.; Yucel, E.; Cicek, G.; Kayir, O.; Aksit, H.; Telci, I.; Guzel, A. J. New Results Sci. 2014, 7 (7), 1-6.
  • 6. Türkmen, N.; Öz, A.; Sönmez, A.; Erol, T.; Gülümser, D.; Yurdakul, B.; Kayır, Ö.; Elmastas, M.; Erenler, R. J. New Results Sci. 2014, 6 (6), 27-31.
  • 7. Saidi, A.; Hambaba, L.; Kucuk, B.; Cacan, E.; Erenler, R. Curr. Bioact. Compd. 2022, 18 (3), 72-83.
  • 8. Koysu, P.; Genc, N.; Elmastas, M.; Aksit, H.; Erenler, R. Nat. Prod. Res. 2019, 33 (24), 3592-3595.
  • 9. Erenler, R.; Telci, I.; Ulutas, M.; Demirtas, I.; Gul, F.; Elmastas, M.; Kayir, O. J. Food Biochem. 2015, 39 (5), 622-630.
  • 10. Dede, E.; Genc, N.; Elmastas, M.; Aksit, H.; Erenler, R. Nat. Prod. J. 2019, 9 (3), 238-243.
  • 11. Erenler, R.; Nusret, G.; Elmastaş, M.; Eminağaoğlu, Ö. Turk. J. Biodiv. 2019, 2 (1), 13-17.
  • 12. Nusret, G.; Elmastas, M.; Telci, I.; Erenler, R. Int. J. Chem. Technol. 2020, 4 (2), 179-184.
  • 13. Aydin, A.; Erenler, R.; Yılmaz, B.; Tekin, Ş. J. Turk. Chem. Soc., Sec A: Chem 2016, 3 (3), 217-228.
  • 14. Elmastas, M.; Erenler, R.; Isnac, B.; Aksit, H.; Sen, O.; Genc, N.; Demirtas, I. Nat. Prod. Res. 2016, 30 (3), 299-304.
  • 15. Gecer, E. N. J. Inorg. Organomet. Polym. Mater. 2021, 31 (11), 4402-4409.
  • 16. Gecer, E. N.; Erenler, R.; Temiz, C.; Genc, N.; Yildiz, I. Particul. Sci. Technol. 2021, 40 (1), 50-57.
  • 17. Genc, N. Particul. Sci. Technol. 2021, 39 (5), 562-568.
  • 18. Genc, N.; Yildiz, I.; Chaoui, R.; Erenler, R.; Temiz, C.; Elmastas, M. Inorg. Nano-Met. Chem. 2021, 51 (3), 411-419.
  • 19. Burlacu, E.; Tanase, C.; Coman, N.-A.; Berta, L. Molecules 2019, 24 (23), 4354.
  • 20. de Souza, T. A. J.; Souza, L. R. R.; Franchi, L. P. Ecotox. Environ. Safe. 2019, 171, 691-700.
  • 21. El-Seedi, H. R.; El-Shabasy, R. M.; Khalifa, S. A.; Saeed, A.; Shah, A.; Shah, R.; Iftikhar, F. J.; Abdel-Daim, M. M.; Omri, A.; Hajrahand, N. H. RSC Adv. 2019, 9 (42), 24539-24559.
  • 22. Faraz, A.; Faizan, M.; Sami, F.; Siddiqui, H.; Pichtel, J.; Hayat, S. IET Nanobiotech. 2019, 13 (4), 345-352.
  • 23. Ökten, S.; Çakmak, O.; Erenler, R.; Yüce, Ö.; Tekin, S. Turk. J. Chem. 2013, 37 (6), 896-908.
  • 24. G Ravelo, A.; Estévez-Braun, A.; Chávez-Orellana, H.; Pérez-Sacau, E.; Mesa-Siverio, D. Curr. Top. Med. Chem. 2004, 4 (2), 241-265.
  • 25. Erenler, R.; Meral, B.; Sen, O.; Elmastas, M.; Aydin, A.; Eminagaoglu, O.; Topcu, G. Pharm. Biol. 2017, 55 (1), 1646-1653.
  • 26. Elmastas, M.; Celik, S. M.; Genc, N.; Aksit, H.; Erenler, R.; Gulcin, İ. Int. J. Food Prop. 2018, 21 (1), 374-384.
  • 27. Erenler, R.; Demirtas, I.; Karan, T.; Gul, F.; Kayir, O.; Karakoc, O. C. Trends Phytochem. Res. 2018, 2 (2), 91-96.
  • 28. Karan, T.; Simsek, S.; Yildiz, I.; Erenler, R. Int. J. Sec. Metabol. 2018, 5 (2), 87-93.
  • 29. Erenler, R.; Sen, O.; Aksit, H.; Demirtas, I.; Yaglioglu, A. S.; Elmastas, M.; Telci, İ. J. Sci. Food Agr. 2016, 96 (3), 822-836.
  • 30. Erenler, R.; Dag, B. Inorg. Nano-Met. Chem. 2022, 52 (4), 485-492.
  • 31. Sahin Yaglioglu, A.; Akdulum, B.; Erenler, R.; Demirtas, I.; Telci, I.; Tekin, S. Med. Chem. Res. 2013, 22 (6), 2946-2953.
  • 32. Erenler, R.; Pabuccu, K.; Yaglioglu, A. S.; Demirtas, I.; Gul, F. Z. Naturforsch. C 2016, 71 (3-4), 87-92.
  • 33. Erenler, R.; Sen, O.; Yaglioglu, A. S.; Demirtas, I. Comb. Chem. High. T. Scr. 2016, 19 (1), 66-72.
  • 34. Erenler, R.; Sen, O.; Yildiz, I.; Aydın, A. Rec. Nat. Prod. 2016, 10 (6), 766-770.
  • 35. Karan, T.; Erenler, R.; Bozer, B. M. Z. Naturforsch. C 2022.
  • 36. Hu, W.; Kavanagh, J. J. Lancet Oncol. 2003, 4 (12), 721-729.
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kimya Mühendisliği
Bölüm Makale
Yazarlar

Ramazan Erenler 0000-0002-0505-3190

Esma Nur Geçer 0000-0002-0095-079X

Büşra Moran Bozer 0000-0002-7280-4417

Yayımlanma Tarihi 31 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 6 Sayı: 2

Kaynak Göster

APA Erenler, R., Geçer, E. N., & Moran Bozer, B. (2022). Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract. International Journal of Chemistry and Technology, 6(2), 142-146. https://doi.org/10.32571/ijct.1187754
AMA Erenler R, Geçer EN, Moran Bozer B. Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract. Int. J. Chem. Technol. Aralık 2022;6(2):142-146. doi:10.32571/ijct.1187754
Chicago Erenler, Ramazan, Esma Nur Geçer, ve Büşra Moran Bozer. “Cytotoxic, Apoptotic, and Necrotic Effects of Silver Nanoparticles Biosynthesized Using Origanum Majorana Extract”. International Journal of Chemistry and Technology 6, sy. 2 (Aralık 2022): 142-46. https://doi.org/10.32571/ijct.1187754.
EndNote Erenler R, Geçer EN, Moran Bozer B (01 Aralık 2022) Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract. International Journal of Chemistry and Technology 6 2 142–146.
IEEE R. Erenler, E. N. Geçer, ve B. Moran Bozer, “Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract”, Int. J. Chem. Technol., c. 6, sy. 2, ss. 142–146, 2022, doi: 10.32571/ijct.1187754.
ISNAD Erenler, Ramazan vd. “Cytotoxic, Apoptotic, and Necrotic Effects of Silver Nanoparticles Biosynthesized Using Origanum Majorana Extract”. International Journal of Chemistry and Technology 6/2 (Aralık 2022), 142-146. https://doi.org/10.32571/ijct.1187754.
JAMA Erenler R, Geçer EN, Moran Bozer B. Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract. Int. J. Chem. Technol. 2022;6:142–146.
MLA Erenler, Ramazan vd. “Cytotoxic, Apoptotic, and Necrotic Effects of Silver Nanoparticles Biosynthesized Using Origanum Majorana Extract”. International Journal of Chemistry and Technology, c. 6, sy. 2, 2022, ss. 142-6, doi:10.32571/ijct.1187754.
Vancouver Erenler R, Geçer EN, Moran Bozer B. Cytotoxic, apoptotic, and necrotic effects of silver nanoparticles biosynthesized using Origanum majorana extract. Int. J. Chem. Technol. 2022;6(2):142-6.
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