Review
BibTex RIS Cite

Bitki Bazlı Hammaddelerdeki Biyoaktif Bileşiklerin Elde Edilmesi İçin Ekstraksiyon Yöntemlerinin İncelenmesi

Year 2023, Volume: 25 Issue: 3, 492 - 513, 15.12.2023
https://doi.org/10.24011/barofd.1303285

Abstract

Son yıllarda lignoselülozik biyokütlelerin takviye gıda ürünlerindeki kullanımı popüler hale gelmiştir. Lignoselülozik biyokütlelerdeki bu etkin bileşenlerin ekstraksiyonunda güvenilir ve kısa süreli yöntemlerin geliştirilmesi ve doğa dostu çözücülerin kullanılması yönünde yapılan çalışmalar artış göstermektedir. Geleneksel ekstraksiyon yöntemlerinin süreleri oldukça uzun olmakta ve çok miktarda organik çözücü kullanılmaktadır. Ayrıca kullanılan organik çözücülerin çevreye olan zararı da oldukça fazladır. Bu sebepten ekstraksiyon süresini düşüren, organik çözücü ve doğa dostu “yeşil kimya” çözücülerin kullanım miktarını azaltan teknolojilere ihtiyaç günden güne artmaktadır. Bu derleme çalışmasında, geleneksel ve modern ekstraksiyon yöntemleri incelenmiş ve bu yöntemlerin genel uygulama alanları ortaya konulmuştur. Maserasyon, presleme, infüzyon, çürütme, süzülme, kaynatma, reflüks, tentür, distilasyon ve sokslet metotlarının olduğu geleneksel ekstraksiyon yöntemleri ile basınçlı sıvı ekstraksiyon, süperkritik sıvı ekstraksiyon, ultrasonik destekli ekstraksiyon, mikrodalga destekli ekstraksiyon, darbeli elektrik alan ekstraksiyonu, enzim destekli ekstraksiyon metotlarının yer aldığı modern ekstraksiyon yöntemlerinin çeşitleri ve değişkenlik gösteren parametreleri araştırılmıştır. Yapılan incelemeler neticesinde modern ekstraksiyon yöntemlerinin geleneksel yöntemlere nazaran, daha az miktarda örnek, daha düşük hacimde çözücü, daha düşük enerji sarfiyatı ve daha kısa ekstraksiyon sürelerinde gerçekleştirildiği görülmüştür. Çalışma kapsamında, tüm bunlar göz önünde bulundurulduğunda modern ekstraksiyon yöntemlerinin geleneksel yöntemlere göre daha uygulanabilir doğa dostu yöntemler olduğu belirlenmiştir.
Maserasyon, presleme, infüzyon, çürütme, süzülme, kaynatma, reflüks, tentür, distilasyon ve sokslet metotlarının olduğu geleneksel ekstraksiyon yöntemleri ile basınçlı sıvı ekstraksiyon, süperkritik sıvı ekstraksiyon, ultrasonik destekli ekstraksiyon, mikrodalga destekli ekstraksiyon, darbeli elektrik alan ekstraksiyonu, enzim destekli ekstraksiyon metotlarının yer aldığı modern ekstraksiyon yöntemlerinin çeşitleri ve değişkenlik gösteren parametreleri araştırılmıştır. Yapılan incelemeler neticesinde modern ekstraksiyon yöntemlerinin geleneksel yöntemlere nazaran, daha az miktarda örnek, daha düşük hacimde çözücü, daha düşük enerji sarfiyatı ve daha kısa ekstraksiyon sürelerinde gerçekleştirildiği görülmüştür. Çalışma kapsamında, tüm bunlar göz önünde bulundurulduğunda modern ekstraksiyon yöntemlerinin geleneksel yöntemlere göre daha uygulanabilir doğa dostu yöntemler olduğu belirlenmiştir.

References

  • Abegunde, S. M., Ayodele-Oduola, R. O. (2015). Comparison of Efficiency of Different Solvents Used for the Extraction of Phytochemicals from the Leaf, Seed and Stem Bark of Calotropis Procera. International Journal of Science and Research (IJSR), 4(7), 835-838.
  • Abd Aziz, N. A., Hasham, R., Sarmidi, M. R., Suhaimi, S. H., Idris, M. K. H. (2021). A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study on Orthosiphon aristatus, Eurycoma longifolia and Andrographis paniculata. Saudi Pharmaceutical Journal, 29, 143-165.
  • Abubakar, A. R., Haque, M. (2020). Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes. Journal of Pharmacy and Bioallied Sciences, 12, 1-10.
  • Agregan, R., Munekata, P. E. S., Feng, X., Astray, G., Gullon, B., Lorenzo, J. M. (2021). Recent advances in the Extraction of Polyphenols from eggplant and their application in foods. LWT – Food Science and Technology, 146, 111381.
  • Ağçam, E., Akyıldız, A., Akdemir Evrendilek, G. (2014). Vurgulu Elektrik Alan Teknolojisi (PEF): Sistem ve Uygulama Odacıkları. Academic Food Journal, 12(2), 69-78.
  • Akdağ, A. & Öztürk, E. (2019). Distillation Methods of Essential Oils. Selçuk Üniversitesi Fen Fakültesi Dergisi, 45 (1), 22-31.
  • Alara, O. R., Abdurahman, N. H., Abdul Mudalip, S. K. & Olalere, O. A. (2018). Microwave-assisted extraction of vernonia amygdalina leaf for optimal recovery of total phenolic content. Journal of Applied Research On Medicinal and Aromatic Plants, 10, 16-24.
  • Alara, O. R., Abdurahman, N. H., Ukaegbu, C. I. (2021). Extraction of phenolic compounds: A review. Current Research in Food Science, 4, 200-214.
  • Alma, M. H., Çetin, N. S. (2002). Orman Foliagesi Üzerinde Etkili Olan Faktörler ve Foliagenin Kullanım Yerleri. II. Ulusal Karadeniz Ormancılık Kongresi, Artvin, 1049-1056.
  • Antosz, K., Machado, J., Mazurkiewicz, D., Antonelli, D., Soares, F. (2022). Systems Engineering: Availability and reliability. Applied sciences, 12, 2504.
  • Ashton, L., Warwick, P., Giddings, D. (1999). The Measurement of 36Cl and 129I in concrete wastes. The Analyst, 124(4), 627-632.
  • Avan, M. (2021). Türkiye’de ve Dünya’da görülen önemli tıbbi ve aromatik bitkiler, özellikleri ve hastalıkları üzerine araştırmalar. Uluslararası Doğu Anadolu Fen Mühendislik ve Tasarım Dergisi, 3(1), 129-156.
  • Avşar, G., Topallar, S., Özdemir, S., Külekçi, B. (2014). Uçucu Bileşen İçeren Bitkilerden Süperkritik Ekstraksiyon Yöntemi ile Özütleme. 4. Kozmetik Kimyası, Üretimi, Standardizasyonu Kongresi, Kimyagerler Derneği, 14-16 Şubat, Antalya.
  • Azmir, J., Zaidul, I. S. M., Rahman, M. M., Sharif, K. M., Mohamed, A., Sahena, F., Jahurul, M. H. A., Ghafoor, K., Norulaini, N. A. N., Omar, A. K. M. (2013). Techniques for extraction of bioactive compounds from plant materials: A review. Journal of Food Engineering, 117, 426-436.
  • Başer, K. H. C. (2010). Tıbbi ve Aromatik Bitkisel Ürünlerin Üretimi ve Kalite Kontrolü, (Ed.). Eskişehir: Anadolu Üniversitesi Yayınları.
  • Belokurov, S. S., Narkevich, I. A., Flisyuk, E. V., Kaukhova, I. E., Aroyan, M. V. (2019). Modern extraction methods for medicinal plant raw material (review). Pharmaceutical Chemistry Journal, 53(6), 48-53.
  • Belwal, T., Ezzat, S. M., Rastrelli, L., Bhatt, I. D., Daglia, M., Baldi, A., P. Devkota, H., E. Orhan, I., K. Patra, J., Das, G., Anandharamakrishnan, C., Gomez-Gomez, L., F. Nabavi, S., M. Nabavi, S., Atanasov, A. G. (2018). A Critical Analysis of Extraction Techniques Used for Botanicals: Trends, Priorities, İndustrial Uses and Optimization Strategies. Trends in Analytical Chemistry, 100, 82-102.
  • Borneo, R., Le´on, A. E., Aguirre, A., Ribotta, P., Cantero, J. J. (2009). Antioxidant capacity of medicinal plants from the Province of C´ordoba (Argentina) and their in vitro testing in a model food system. Food Chem, 112, 664–70.
  • Boukhatem, M. N. (2020). Scientific findings: The amazing use of essential oils and their related terpenes as natural preservatives to ımprove shelf-life of food. Food Sciance &Nutrition Technology, 5, 2574-2701.
  • Bouras, M., Chadni, M., Barba, F.J., Grimi, N., Bals, O., Vorobiev E. (2015). Optimization of microwave-assisted extraction of polyphenols fromQuercus bark. Industrial Crops and Products, 77, 593-601.
  • Büyüktuncel, E. (2012). Gelişmiş ekstraksiyon teknikleri. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, 209-242.
  • Calinescu, I., Vinatoru, M., Ghimpeteanu, D., Lavric, V., Mason, T. J. (2021). Anew reactor for process intensification involving the simultaneous application of adjustable ultrasound and microwave radiation. Ultrasonics Sonochemistry, 77, 105701.
  • Campbell, K. A., Vaca-Medina, G., Glatz, C. E., Pontalier, P. Y. (2016). Parameters affecting enzyme-assisted aqueous extraction of extruded sunflower meal. Food Chem, 208, 245-251.
  • Cellat, K. (2011). Bazı endemik bitkilerin uçucu yağ bileşenlerinin Ekstrakte edilmesi ve içeriklerinin araştırılması. Çukurova Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı Yüksek Lisans Tezi, 73.
  • Chemat, F., Huma, Z., Khan, M. K. (2011). Applications of ultrasound in food technology: processing, preservation and extraction. Ultrasonics Sonochemistry, 18, 813-835.
  • Chemat, F., Rombaut, N., Sicaire, A. G., Meullemiestre, A., Fabiano Tixier, A. S., Abert Vian, M. (2017). Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review. Ultrasonics Sonocchemistry, 34, 540-560.
  • Chen, H., Zhou, X., Zhang, J. (2014). Optimization of enzyme assisted extraction of polysaccharides from Astragalus membranaceus. Carbohydrate Polymers, 111, 567-575.
  • Chu, L. S., Latiff, N. A., Mohamad, M. (2016). Reflux extraction and cleanup process by column chromatography for high yield of andrographolide anriched extract. Journal of Applied Research onMedicinal and Aromatic Plants, 3, 64-70.
  • Çopuroglu, Ö. (2013). Niğde Yöresindeki Bazı Endemik Bitki Türlerinin Antimikrobiyal Aktiviteleri. Niğde Üniversitesi Fen Bilimleri Enstitüsü Biyoloji Anabilim Dalı Yüsek Lisans Tezi, 67.
  • Daud, N. M., Putra, N. R., Jamaludin, R., Norodin, N. S. Md., Sarkawi, N. S., Hamzah, M. H. S., Nasir, H. M., Zaidel, D. N. A., Yunus, M. A. C., Salleh, L. Md. (2022). Valorisation of plant seed as natural bioactive compounds by various Extraction methods: A review. Trends in Food Science & Technology, 119, 201-214.
  • De Azevedo, A. B. A., Kieckbush, T. G., Tashima, A. K., Mohamed, R. S., Mazzafera, P., de Melo, S. A. B. V. (2008). Extraction of green coffee oil using supercritical carbon dioxide. Journal of Supercritical Fluids, 44 (2), 186.
  • Dedebaş, T., Dursun Çapar, T., Ekici, L., Yalçın, H. (2021). Yağlı tohumlarda ultrasonik destekli ekstraksiyon yöntemi ve avantajları. Avrupa Bilim ve Teknoloji Dergisi, 21, 313-322.
  • De Castro, M. D. L., Priego-Capote, F. (2010). Soxhlet extraction. Past and present panacea. Journal of Chromatography A, 1217 (16), 2383.
  • Diaconeasa, Z., Iuhas, C. I., Ayvaz, H., Mortas, M., Farcas, A., Mihai, M., Danciu, C., Stanila, A. (2023). Anthocyanins from Agro-Industrial Food Waste: Geographical Approach and Methods of Recovery-A Review. Plants, 12, 74.
  • Diestra, K. V., Vandenberghe, L. P. S., Soccol, C. R. (2020). Oilseed Enzymatic Preatreatment for Efficient Oil Recovery in Biodiesel Production Industry: a Review. BioEnergy Research, 13, 1016-1030.
  • Dönmez, İ. E., Hemming, J., Willför, S. (2016). Bark extractives and suberin monomers from arbutus andrachne and platanus orientalis. BioRes, 11 (1), 2809-2819.
  • Eisenmenger, M., Dunford, N. T. (2008). Bioactive components of commercial and supercritical carbon dioxide processed wheat germ oil. Journal of the American Oil Chemists Society, 85 (1), 55.
  • Elguea-Culebras, G. O. de, Bravo, E. M., Sanchez-Vioque, R. (2022). Potential sources and methodologies for the recovery of phenolic compounds from distillation residues of Mmediterranean aromatic plants. An approach to the valuation of by-products of the essential oil market. Iındustrial Crops & Products, 175, 114261.
  • El Maaiden, E., Bouzroud, S., Nasser, B., Moustaid, K., Mouttaqi, A. E., Ibourki, M., Boukcim, H., Hirich, A., Kouisni, L., El Kharrassi, Y. (2022). A comparative study between conventional and advanced extraction techniques: pharmaceutical and cosmetic properties of plant extracts. Molecules, 27, 2074.
  • Ercan, S. Ş., Soysal, Ç. (2011). Ultrasonun Gıdalarda ve Enzimlerin İnaktivasyonunda Kullanılması. Gıda/The Journal of Food, 36 (4), 225-231.
  • Ergen, N., Coşkun, S. H., Orhan, D. D., Aslan, M., Sezik, E., Atalay, A. (2018). Evaluation of the lifespan extension effects of several Turkish medicinal plants in Caenorhabditis elegans. Turkish Journal of Biology, 42(2), 163–173.
  • Famiyeh, L., Chen, K., Xu, J., Sun, Y., Guo, Q., Wang, C., Lv, J., Tang, Y., Yu, H., Snape, C., He, J. (2021). A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycylic aromatic hydrocarbons. Science of the Total Environment, 789, 147741.
  • Fu, X., Wang, D., Belwal, T., Xie J., Xu, Y., Li, L., Zou, L., Zhang, L., Luo, Z. (2021). Natural deep eutectic solvent enhanced pulse-ultrasonication assisted Extraction as a multi-stability protective and efficient green strategy to extract anthocyanin from blueberry pomace. LWT – Food Science and Technology, 144, 111220.
  • Gavahian, M., Farahnaky, A. (2018). Ohmic-assisted hydrodistillation technology: A review. Trends in Food Science &Technology, 72, 153-161.
  • George, M. J., Sichilongo, K. F., Ramabulana, T., Madala, N. E., Dubery, I. A. (2019). Comparison of soxhlet and reflux techniques for extraction and characterisation of potential endocrine-disrupting compounds from solid waste dumpsite soil. Environ. Monit Assess, 191, 149.
  • Geramitcioski, T., Mitrevski, V., Mijakovski, V. (2018). Design of a small press for extracting essential oil according VDI 2221. IOP Conference Sseries: Materials Science and Engineering, 393.
  • Guntero, V. A., Mancini, P. M., Kneeteman, M. N. (2017). Introducing Organic Chemistry Students to the Extraction of Natural Products Found in Vegetal Species. World Journal of Chemical Education, 5, 142-147.
  • Haji-Moradkhani, A., Rezaei, R., Moghimi, M. (2018). Optimization of pulsed electric field-assisted oil extraction from cannabis seeds. Journal of Food Process Engineering, 42, 13028.
  • Handa, S. S., Khanuja, S. P. S., Longo, G., Rakesh, D. D. (2008). Extraction Technologies for Medicinal and Aromatic Plants. International Centre for Science and High Technology, Trieste.
  • Hasinah Johari, S. N., Fazalul Rahiman, M. H., Adnan, R., Tajjudin, M. (2020). Real-time IMC-PID control and monitoring of Essential oil Extraction process using loT. In Proceedings of the 2020 IEEE International Conference on Automatic Control and Intelligent Systems (12CASIS), Malaysia, pp. 51-56.
  • Homestead and chill, (n.d.). Retrieved from https://homesteadandchill.com/homemade-cannabis-tincture-recipe/
  • Hussain, M. K., Saquib, M., Khan, M. F. (2019). Techniques for extraction, isolation, and standardization of bio-active compounds from medicinal plants. In Natural Bio-active compounds (pp. 179–200). Singapore: Springer.
  • Ingle, K. P., Deshmukh, A. G., Padole, D. A., Dudhare, M. S., Moharil, M. P., Khelurkar, V. C. (2017). Phytochemicals: Extraction methods, identification and detection of bioactive compounds from plant extracts. Journal of Pharmacognosy and Phytochemistry, 6(1), 32-36.
  • İmer, Y., Taşan, M., (2018). Çeşitli soğuk pres yağların bazı mikro ve makro element içeriklerinin belirlenmesi. Tekirdağ Ziraat Fakültesi Dergisi, 15 (01), 14-25.
  • Jha, A. K., Sit, N. (2022). Extraction of bioactive compounds from plant materials using combination of various novel methods: A review. Trends in Food Science &Technology, 119, 579-591.
  • Kant, R., Kumar, A. (2022). Review on Essential oil Extraction from aromatic and medicinal plants: Techniques, performance and economic analysis. Sustainable Chemistry and Ppharmacy, 30, 100829.
  • Karabaş, H. (2013). Soğuk pres ve solvent ekstraksiyon teknikleri ile üretilen aspir yağı ve aspir biyodizellerinin yağ ve yakıt özelliklerinin incelenmesi. 28. Ulusal Tarımsal Mekanizasyon Kongresi, 4-6 Eylül, Konya, Türkiye, 30-36.
  • Kaufmann, B., Christen, P. (2002). Recent extraction techniques for natural products: microwaveassisted extraction and pressurised solvent extraction. Phytochemical analysis, 13, 105–113.
  • Kaya, D., Ergönül, P. G. (2015). Obtaining methods of volatile oils. GIDA-Journal of Food, 40 (5), 303-310.
  • Kongkiatpaiboon, S., Gritsanapan, W. (2013). Optimized extraction for high yield of insecticidal didehydrostemofoline alkaloid in Stemona collinsiae root extracts. Industrial Crops and Products, 41, 371-374.
  • Kumar, P., Yadav, D., Kumar, P., Panesar, P. S., Bunkar, D. S., Mishra, D., Chopra, H. K. (2016). Comparative study on conventional, ultrasonication and microwave assisted extraction of γ-oryzanol from rice bran. Journal of Food Science Technology, 53, 2047-2053.
  • Kumar, A., Nirmal, P., Kumar, M., Jose, A., Tomer, V., Oz, E., Proestos, C., Zeng, M., Elobeid Oz, F. (2023). Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method. Molecules, 28, 887.
  • Lakka, A., Bozinou, E., Makris, D. P., Lalas, S. L. (2021). Evaluation of Pulsed Electric Field Polyphenol Extraction from Vitis vinifera, Sideritis scardica and Crocus sativus. Chemengineering, 5, 25.
  • Liu, T., Sui, X., Li, L., Zhang, J., Liang, X., Li, W., Zhang, H. (2016). Application of ionic liquids based enzyme-assisted extraction of chlorogenic acid from Eucommia ulmoides leaves. Analytica Chimica Acta, 903, 91-99.
  • Liu, Z., Esveld, E., Vincken, J., Bruins, M. E. (2019). Pulsed Electric Field as an Alternative Pre-treatment for Drying to Enhance Polyphenol Extraction from Fresh Tea Leaves. Food and Bioprocess Technology, 12, 183-192.
  • Machado, C. A., Oliveira, F. O., de Andrade, M. A., Saraiva Hodel, K. V., Lepikson, H., Souza Machado, B. A. (2022). Steam distillation for essential oil extraction: An evaluation of technological advances based on ana analysis of patent documents. Sustainability, 14, 7119.
  • Maier, T., Schieber, A., Kammerer, D. R., Carle, R. (2009). Residues of grape (Vitis vinifera L.) seed oil production as a valuable source of phenolic antioxidants. Food Chem, 112, 551-559.
  • Majekodunmi, S. O. (2015). Review of extraction of medicinal plants for pharmaceutical research. Merit research journal of medicine and medical sciences, 3(11), 521-527.
  • Memarzadeh, S. M., Gholami, A., Pirbalouti, A. G., Masoum, S. (2020). Bakhtiari savory (Satureja bachtiarica Bunge.) essential oil and its chemical profile, antioxidant activities, and leaf micromorphology under green and conventional extraction techniques. Industrial Crops & Products, 154, 112719.
  • Mohan, K., Ganesan, A. R., Ezhilarasi, P. N., Kondamareddy, K. K., Rajan, D. K., Sathishkumar, P., Rajarajeswaran, J., Conterno, L. (2022). Green and eco-friendly approaches for the extraction of chitin and chitosan: A review. Arbohydrate Polymers, 287, 119349.
  • Mousavi, S. A., Nateghi, L., Dakheli, M. J., Ramezan, Y., Piravi-Vanak, Z. (2022). Maceration and ultrasound-assisted methods used for Extraction of phenolic compounds and Antioxidant activity from Ferulago angulata. Journal of Food Processing and Preservation, 46 (3), 16356.
  • Mustafa, A., Turner, C. (2011). Pressurized liquid extraction as a green approach in food and herbal plants extraction: A review. Analytica Chimica Acta, 703 (1), 8.
  • Olaiya, N. G., Oyekanmi, A. A., Hanafiah, M. M., Olugbade, T. O., Adeyeri, M. K., Olaiya, F. G. (2022). Enzyme-assisted extraction of nanocellulose from textile waste: A review on production technique and applications. Bioresource Technology Reports, 19, 101183.
  • Oluwaseun, R. A., Nour, H. A., Chinonso, I. U. (2018). Soxhlet extraction of phenolic compounds from Vernonia cinerea leaves and its antioxidant activity. Journal of Applied Research on Medicinal and Aromatic Plants, 11, 12-17.
  • Oprescu, E. E., Enascuta, C. E., Radu, E., Ciltea-Udrescu, M., Lavric, V. (2022). Does the ultrasonic field improve the Extraction productivity compared to classical methods – Maceration and reflux distillation? Chemical Engineering and Processing – Process Intensification, 179, 109082.
  • Özer, Z., Kılıç, T., Çarıkçı, S., Yılmaz, H. (2018). Investigation of phenolic compounds and antioxidant activity of Teucrium polium L. decoction and infusion. J. BAUN Inst. Sci. Tchnol., 20(1), 212-218.
  • Öztekin, S., Soysal, Y. (1998). Tıbbi ve Aromatik Bitkilerde Ekstraksiyon Yöntemi. Tarımsal Mekanizasyon 18. Ulusal Kongresi, Tekirdağ, 731-745.
  • Pawliszyn, J. (2003). Sample preparation: ouo vadis? Analytical Chemistry, 75 (11), 2543.
  • Radosevic, K., Bubalo, M. C., Srcek, V. G., Grgas, D., Dragicevic, T. L., Redovnikavic, I. R. (2015). Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents. Ecotoxicology and Environmental Safety, 112, 46-53.
  • Radwan, M. N., Morad, M. M., Ali, M. M., Wasfy, K. I. (2020). Extraction of peppermint volatile oil using a simple constructed steam distillation system. Plant Archives, 20, 1487-1491.
  • Rasul, M. G. (2018). Extraction, Isolation and Characterization of Natural Products from medicinal Plants. International Journal of Basic Sciences and Applied Computing (ıjbsac), 2, 6.
  • Richter, B. E., Jones, B. A., Ezzell, J. L., Porter, N. L., Avdalovic, N., Pohl, C. (1996). Accelerated solvent extraction: A technique for sample preparation. Analytical Chemistry, 68 (6), 1033.
  • Rodrigues, L. G. G., Mazzutti, S., Siddique, I., da Silva, M., Vitali, L., Ferreira, S. R. S. (2020). Subcritical water extraction and microwave-assisted extraction applied for the recovery of bioactive components from Chaya (Cnidoscolus aconitifolius Mill.) The Journal of Supercritical Fluids, 165, 104976.
  • Saim, N., Dean, J. R., Abdullah, M. P., Zakaria, Z. (1997). Extraction of polycyclic aromatic hydrocarbons from contaminated soil using soxhlet extraction, pressurised and atmospheric microwave-assisted extraction, supercritical fluid extraction and accelerated solvent extraction. Journal of Chromatography A, 791 (2), 361.
  • Samaram, S., Mirhosseini, H., Tan, C. P., Ghazali, H. M. (2013). Ultrasound-assisted extraction and solvent extraction of papaya seed oil: Crystallization and thermal behavior, saturation degree, color and oxidative stability. Ind Crops Prod, 52, 702-708.
  • Sasıkala, M., Sundaraganapathy, R. (2017). Preliminary Phytochemical Evaluation of Hydroalcoholic Extract of Ipomoea Aquatica Forssk. From Alıyar Riverinein South India. International Journal of Pharma and Bio Sciences, 8(3), 356-365.
  • Song, Y., Han, A., Park, S., Cho, C., Rhee, Y., Hong, H. (2020). Effect of enzyme-assisted extraction on the physicochemical properties and bioactive potential of lotus leaf polysaccharides. International Journal of Biological Macromolecules, 153, 169-179.
  • Spigno, G., De Faveri, D. (2009). Microwave-assisted extraction of tea phenols: a phenomenological study. Journal of Food Engineering, 93, 210-217.
  • Strati, I. F., Gogou, E., Oreopoulou, V. (2015). Enzyme and high pressure assisted extraction of carotenoids from tomato waste. Food and Bioproducts Processing, 94, 668-674.
  • Şahin, Ö. (2019). Determination of components of extracted from different parts of melocan (smilax excelsa L.) plant by microwave and ultrasonic assisted extraction. Hacettepe Üniversitesi, Gıda Mühendisliği Anabilim Dalı Yüksek Lisans Tezi, 125.
  • Tadeo, J. L., Sanchez-Brunete, C., Albero, B., Garcia-Valcarcel, A. I. (2010). Application of ultrasound- assisted extraction to the determination of contaminants in food and soil samples. Journal of Chromatography A, 1217 (16), 2415.
  • Tiring, G., Satar, S., Özkaya, O. (2021). Sekonder Metabolitler. Journal of Agricultural Faculty of Bursa Uludağ University, 35(1), 203-215.
  • Tokkan, D., Kuşlu, S., Çalban, T., Çolak, S. (2012). Anod Çamurundaki Gümüşün Amonyum Tiyosülfat Çözeltilerinde Mikrodalga Enerjisi ile Ekstraksiyonunun Optimizasyonu. Onuncu Ulusal Kimyasal Mühendisliği Kongresi, Koç Üniversitesi, İstanbul, 3-6 Eylül.
  • Vurdu, H., (1989), Pinus nigra Arnold Foliage. Journal of Islamic Academy of Sciences, 2, 106-108.
  • Wen, C., Zhang, J., Zhang, H., Dzah, C. S., Zandile, M., Duan, Y., Ma, H., Luo X. (2018). Advances in ultrasound assisted extraction of bioactive compounds from cash crops. Ultrasonics-Sonochemistry, 48, 538-549.
  • Xavier, V. B., Vargas, R. M. F., Cassel, E., Lucas, A. M., Santos, M. A., Mondin, C. A., Santarem, E. R., Astarita, L. V., Sartor, T. (2011). Mathematical modeling for extraction of essential oil from Baccharis spp. by steam distillation. Ind. Crop. Prod., 33, 599-604.
  • Yılmaz, F. M., Özer, P., Görgüc, A. (2018). Mikrodalga teknolojisinin bitkisel dokulardan makro ve mikro bileşenlerin özütlenmesinde kullanımı. Gıda/The Journal of Food, 43, 765-775.
  • Yusoff, I. M., Taher, Z. M., Rahmat, Z., Chua, L. S. (2022). Areview of ultrasound-assisted Extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins. Food Research International, 157, 111268.
  • Zhang, Q. W., Lin, L. G., Ye, W. C. (2018). Ttechniques for extraction and isolation of natural products: a comprehensive review. Chinese Mmedicine, 13,20.
  • Zhang, W. L., Chen, J. P., Lam, K. Y., Zhan, J. Y., Yao, P., Dong, T. T., Tsim, K. W. (2014). Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture. Evidence-Based Complementary and Alternative Medicine, 608721.
  • Zougagh, M., Valcarcel, M., Rios, A. (2004). Supercritical fluid extraction: a critical review of its analytical usefulness. Trac-Trends in Analytical Chemistry, 23 (5), 399.

A Review of Extraction Methods for Obtaining Bioactive Compounds in Plant-Based Raw Materials

Year 2023, Volume: 25 Issue: 3, 492 - 513, 15.12.2023
https://doi.org/10.24011/barofd.1303285

Abstract

In recent years, the usage of lignocellulosic biomasses in food supplements has become popular. The studies about the development of reliable and short-term methods in the extraction of these active components in lignocellulosic biomasses and the usage of eco-friendly solvents have increased gradually. Traditional extraction methods take a long time and use a large amounts of organic solvents. In addition, the damages of used organic solvents to the environment are high considerably. For this reason, the need for technologies that reduce the extraction time and reduce the use of organic solvents and environmentally friendly "green chemistry" solvents is increasing day by day. In this review, traditional and modern extraction methods were examined and general application areas of these methods were introduced. Traditional extraction methods include maceration, pressing, infusion, digestion, percolation, decoction, reflux, tincture, distillation, and soxhlet methods, and modern extraction methods including pressurized liquid extraction, supercritical fluid extraction, ultrasonic assisted extraction, microwave assisted extraction, pulsed electric field extraction, enzyme assisted extraction methods, and their variation parameters were investigated. It has been seen that modern extraction methods are performed in less amount of sample, lower volume of solvent, lower energy consumption, and shorter extraction times compared to traditional methods. Within the scope of the study, considering all these, it has been determined that modern extraction methods are more applicable to nature-friendly methods than traditional methods.
Traditional extraction methods including maceration, pressing, infusion, digestion, percolation, decoction, reflux, tincture, distillation, and soxhlet methods and modern extraction methods including pressurized liquid extraction, supercritical fluid extraction, ultrasonic assisted extraction, microwave assisted extraction, pulsed electric field extraction, enzyme assisted extraction methods and their variation parameters were investigated. It has been seen that modern extraction methods are performed in less amount of sample, lower volume of solvent, lower energy consumption and shorter extraction times compared to traditional methods. Within the scope of the study, considering all these, it has been determined that modern extraction methods are more applicable nature-friendly methods than traditional methods.

References

  • Abegunde, S. M., Ayodele-Oduola, R. O. (2015). Comparison of Efficiency of Different Solvents Used for the Extraction of Phytochemicals from the Leaf, Seed and Stem Bark of Calotropis Procera. International Journal of Science and Research (IJSR), 4(7), 835-838.
  • Abd Aziz, N. A., Hasham, R., Sarmidi, M. R., Suhaimi, S. H., Idris, M. K. H. (2021). A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study on Orthosiphon aristatus, Eurycoma longifolia and Andrographis paniculata. Saudi Pharmaceutical Journal, 29, 143-165.
  • Abubakar, A. R., Haque, M. (2020). Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes. Journal of Pharmacy and Bioallied Sciences, 12, 1-10.
  • Agregan, R., Munekata, P. E. S., Feng, X., Astray, G., Gullon, B., Lorenzo, J. M. (2021). Recent advances in the Extraction of Polyphenols from eggplant and their application in foods. LWT – Food Science and Technology, 146, 111381.
  • Ağçam, E., Akyıldız, A., Akdemir Evrendilek, G. (2014). Vurgulu Elektrik Alan Teknolojisi (PEF): Sistem ve Uygulama Odacıkları. Academic Food Journal, 12(2), 69-78.
  • Akdağ, A. & Öztürk, E. (2019). Distillation Methods of Essential Oils. Selçuk Üniversitesi Fen Fakültesi Dergisi, 45 (1), 22-31.
  • Alara, O. R., Abdurahman, N. H., Abdul Mudalip, S. K. & Olalere, O. A. (2018). Microwave-assisted extraction of vernonia amygdalina leaf for optimal recovery of total phenolic content. Journal of Applied Research On Medicinal and Aromatic Plants, 10, 16-24.
  • Alara, O. R., Abdurahman, N. H., Ukaegbu, C. I. (2021). Extraction of phenolic compounds: A review. Current Research in Food Science, 4, 200-214.
  • Alma, M. H., Çetin, N. S. (2002). Orman Foliagesi Üzerinde Etkili Olan Faktörler ve Foliagenin Kullanım Yerleri. II. Ulusal Karadeniz Ormancılık Kongresi, Artvin, 1049-1056.
  • Antosz, K., Machado, J., Mazurkiewicz, D., Antonelli, D., Soares, F. (2022). Systems Engineering: Availability and reliability. Applied sciences, 12, 2504.
  • Ashton, L., Warwick, P., Giddings, D. (1999). The Measurement of 36Cl and 129I in concrete wastes. The Analyst, 124(4), 627-632.
  • Avan, M. (2021). Türkiye’de ve Dünya’da görülen önemli tıbbi ve aromatik bitkiler, özellikleri ve hastalıkları üzerine araştırmalar. Uluslararası Doğu Anadolu Fen Mühendislik ve Tasarım Dergisi, 3(1), 129-156.
  • Avşar, G., Topallar, S., Özdemir, S., Külekçi, B. (2014). Uçucu Bileşen İçeren Bitkilerden Süperkritik Ekstraksiyon Yöntemi ile Özütleme. 4. Kozmetik Kimyası, Üretimi, Standardizasyonu Kongresi, Kimyagerler Derneği, 14-16 Şubat, Antalya.
  • Azmir, J., Zaidul, I. S. M., Rahman, M. M., Sharif, K. M., Mohamed, A., Sahena, F., Jahurul, M. H. A., Ghafoor, K., Norulaini, N. A. N., Omar, A. K. M. (2013). Techniques for extraction of bioactive compounds from plant materials: A review. Journal of Food Engineering, 117, 426-436.
  • Başer, K. H. C. (2010). Tıbbi ve Aromatik Bitkisel Ürünlerin Üretimi ve Kalite Kontrolü, (Ed.). Eskişehir: Anadolu Üniversitesi Yayınları.
  • Belokurov, S. S., Narkevich, I. A., Flisyuk, E. V., Kaukhova, I. E., Aroyan, M. V. (2019). Modern extraction methods for medicinal plant raw material (review). Pharmaceutical Chemistry Journal, 53(6), 48-53.
  • Belwal, T., Ezzat, S. M., Rastrelli, L., Bhatt, I. D., Daglia, M., Baldi, A., P. Devkota, H., E. Orhan, I., K. Patra, J., Das, G., Anandharamakrishnan, C., Gomez-Gomez, L., F. Nabavi, S., M. Nabavi, S., Atanasov, A. G. (2018). A Critical Analysis of Extraction Techniques Used for Botanicals: Trends, Priorities, İndustrial Uses and Optimization Strategies. Trends in Analytical Chemistry, 100, 82-102.
  • Borneo, R., Le´on, A. E., Aguirre, A., Ribotta, P., Cantero, J. J. (2009). Antioxidant capacity of medicinal plants from the Province of C´ordoba (Argentina) and their in vitro testing in a model food system. Food Chem, 112, 664–70.
  • Boukhatem, M. N. (2020). Scientific findings: The amazing use of essential oils and their related terpenes as natural preservatives to ımprove shelf-life of food. Food Sciance &Nutrition Technology, 5, 2574-2701.
  • Bouras, M., Chadni, M., Barba, F.J., Grimi, N., Bals, O., Vorobiev E. (2015). Optimization of microwave-assisted extraction of polyphenols fromQuercus bark. Industrial Crops and Products, 77, 593-601.
  • Büyüktuncel, E. (2012). Gelişmiş ekstraksiyon teknikleri. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, 209-242.
  • Calinescu, I., Vinatoru, M., Ghimpeteanu, D., Lavric, V., Mason, T. J. (2021). Anew reactor for process intensification involving the simultaneous application of adjustable ultrasound and microwave radiation. Ultrasonics Sonochemistry, 77, 105701.
  • Campbell, K. A., Vaca-Medina, G., Glatz, C. E., Pontalier, P. Y. (2016). Parameters affecting enzyme-assisted aqueous extraction of extruded sunflower meal. Food Chem, 208, 245-251.
  • Cellat, K. (2011). Bazı endemik bitkilerin uçucu yağ bileşenlerinin Ekstrakte edilmesi ve içeriklerinin araştırılması. Çukurova Üniversitesi Fen Bilimleri Enstitüsü Kimya Anabilim Dalı Yüksek Lisans Tezi, 73.
  • Chemat, F., Huma, Z., Khan, M. K. (2011). Applications of ultrasound in food technology: processing, preservation and extraction. Ultrasonics Sonochemistry, 18, 813-835.
  • Chemat, F., Rombaut, N., Sicaire, A. G., Meullemiestre, A., Fabiano Tixier, A. S., Abert Vian, M. (2017). Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review. Ultrasonics Sonocchemistry, 34, 540-560.
  • Chen, H., Zhou, X., Zhang, J. (2014). Optimization of enzyme assisted extraction of polysaccharides from Astragalus membranaceus. Carbohydrate Polymers, 111, 567-575.
  • Chu, L. S., Latiff, N. A., Mohamad, M. (2016). Reflux extraction and cleanup process by column chromatography for high yield of andrographolide anriched extract. Journal of Applied Research onMedicinal and Aromatic Plants, 3, 64-70.
  • Çopuroglu, Ö. (2013). Niğde Yöresindeki Bazı Endemik Bitki Türlerinin Antimikrobiyal Aktiviteleri. Niğde Üniversitesi Fen Bilimleri Enstitüsü Biyoloji Anabilim Dalı Yüsek Lisans Tezi, 67.
  • Daud, N. M., Putra, N. R., Jamaludin, R., Norodin, N. S. Md., Sarkawi, N. S., Hamzah, M. H. S., Nasir, H. M., Zaidel, D. N. A., Yunus, M. A. C., Salleh, L. Md. (2022). Valorisation of plant seed as natural bioactive compounds by various Extraction methods: A review. Trends in Food Science & Technology, 119, 201-214.
  • De Azevedo, A. B. A., Kieckbush, T. G., Tashima, A. K., Mohamed, R. S., Mazzafera, P., de Melo, S. A. B. V. (2008). Extraction of green coffee oil using supercritical carbon dioxide. Journal of Supercritical Fluids, 44 (2), 186.
  • Dedebaş, T., Dursun Çapar, T., Ekici, L., Yalçın, H. (2021). Yağlı tohumlarda ultrasonik destekli ekstraksiyon yöntemi ve avantajları. Avrupa Bilim ve Teknoloji Dergisi, 21, 313-322.
  • De Castro, M. D. L., Priego-Capote, F. (2010). Soxhlet extraction. Past and present panacea. Journal of Chromatography A, 1217 (16), 2383.
  • Diaconeasa, Z., Iuhas, C. I., Ayvaz, H., Mortas, M., Farcas, A., Mihai, M., Danciu, C., Stanila, A. (2023). Anthocyanins from Agro-Industrial Food Waste: Geographical Approach and Methods of Recovery-A Review. Plants, 12, 74.
  • Diestra, K. V., Vandenberghe, L. P. S., Soccol, C. R. (2020). Oilseed Enzymatic Preatreatment for Efficient Oil Recovery in Biodiesel Production Industry: a Review. BioEnergy Research, 13, 1016-1030.
  • Dönmez, İ. E., Hemming, J., Willför, S. (2016). Bark extractives and suberin monomers from arbutus andrachne and platanus orientalis. BioRes, 11 (1), 2809-2819.
  • Eisenmenger, M., Dunford, N. T. (2008). Bioactive components of commercial and supercritical carbon dioxide processed wheat germ oil. Journal of the American Oil Chemists Society, 85 (1), 55.
  • Elguea-Culebras, G. O. de, Bravo, E. M., Sanchez-Vioque, R. (2022). Potential sources and methodologies for the recovery of phenolic compounds from distillation residues of Mmediterranean aromatic plants. An approach to the valuation of by-products of the essential oil market. Iındustrial Crops & Products, 175, 114261.
  • El Maaiden, E., Bouzroud, S., Nasser, B., Moustaid, K., Mouttaqi, A. E., Ibourki, M., Boukcim, H., Hirich, A., Kouisni, L., El Kharrassi, Y. (2022). A comparative study between conventional and advanced extraction techniques: pharmaceutical and cosmetic properties of plant extracts. Molecules, 27, 2074.
  • Ercan, S. Ş., Soysal, Ç. (2011). Ultrasonun Gıdalarda ve Enzimlerin İnaktivasyonunda Kullanılması. Gıda/The Journal of Food, 36 (4), 225-231.
  • Ergen, N., Coşkun, S. H., Orhan, D. D., Aslan, M., Sezik, E., Atalay, A. (2018). Evaluation of the lifespan extension effects of several Turkish medicinal plants in Caenorhabditis elegans. Turkish Journal of Biology, 42(2), 163–173.
  • Famiyeh, L., Chen, K., Xu, J., Sun, Y., Guo, Q., Wang, C., Lv, J., Tang, Y., Yu, H., Snape, C., He, J. (2021). A review on analysis methods, source identification, and cancer risk evaluation of atmospheric polycylic aromatic hydrocarbons. Science of the Total Environment, 789, 147741.
  • Fu, X., Wang, D., Belwal, T., Xie J., Xu, Y., Li, L., Zou, L., Zhang, L., Luo, Z. (2021). Natural deep eutectic solvent enhanced pulse-ultrasonication assisted Extraction as a multi-stability protective and efficient green strategy to extract anthocyanin from blueberry pomace. LWT – Food Science and Technology, 144, 111220.
  • Gavahian, M., Farahnaky, A. (2018). Ohmic-assisted hydrodistillation technology: A review. Trends in Food Science &Technology, 72, 153-161.
  • George, M. J., Sichilongo, K. F., Ramabulana, T., Madala, N. E., Dubery, I. A. (2019). Comparison of soxhlet and reflux techniques for extraction and characterisation of potential endocrine-disrupting compounds from solid waste dumpsite soil. Environ. Monit Assess, 191, 149.
  • Geramitcioski, T., Mitrevski, V., Mijakovski, V. (2018). Design of a small press for extracting essential oil according VDI 2221. IOP Conference Sseries: Materials Science and Engineering, 393.
  • Guntero, V. A., Mancini, P. M., Kneeteman, M. N. (2017). Introducing Organic Chemistry Students to the Extraction of Natural Products Found in Vegetal Species. World Journal of Chemical Education, 5, 142-147.
  • Haji-Moradkhani, A., Rezaei, R., Moghimi, M. (2018). Optimization of pulsed electric field-assisted oil extraction from cannabis seeds. Journal of Food Process Engineering, 42, 13028.
  • Handa, S. S., Khanuja, S. P. S., Longo, G., Rakesh, D. D. (2008). Extraction Technologies for Medicinal and Aromatic Plants. International Centre for Science and High Technology, Trieste.
  • Hasinah Johari, S. N., Fazalul Rahiman, M. H., Adnan, R., Tajjudin, M. (2020). Real-time IMC-PID control and monitoring of Essential oil Extraction process using loT. In Proceedings of the 2020 IEEE International Conference on Automatic Control and Intelligent Systems (12CASIS), Malaysia, pp. 51-56.
  • Homestead and chill, (n.d.). Retrieved from https://homesteadandchill.com/homemade-cannabis-tincture-recipe/
  • Hussain, M. K., Saquib, M., Khan, M. F. (2019). Techniques for extraction, isolation, and standardization of bio-active compounds from medicinal plants. In Natural Bio-active compounds (pp. 179–200). Singapore: Springer.
  • Ingle, K. P., Deshmukh, A. G., Padole, D. A., Dudhare, M. S., Moharil, M. P., Khelurkar, V. C. (2017). Phytochemicals: Extraction methods, identification and detection of bioactive compounds from plant extracts. Journal of Pharmacognosy and Phytochemistry, 6(1), 32-36.
  • İmer, Y., Taşan, M., (2018). Çeşitli soğuk pres yağların bazı mikro ve makro element içeriklerinin belirlenmesi. Tekirdağ Ziraat Fakültesi Dergisi, 15 (01), 14-25.
  • Jha, A. K., Sit, N. (2022). Extraction of bioactive compounds from plant materials using combination of various novel methods: A review. Trends in Food Science &Technology, 119, 579-591.
  • Kant, R., Kumar, A. (2022). Review on Essential oil Extraction from aromatic and medicinal plants: Techniques, performance and economic analysis. Sustainable Chemistry and Ppharmacy, 30, 100829.
  • Karabaş, H. (2013). Soğuk pres ve solvent ekstraksiyon teknikleri ile üretilen aspir yağı ve aspir biyodizellerinin yağ ve yakıt özelliklerinin incelenmesi. 28. Ulusal Tarımsal Mekanizasyon Kongresi, 4-6 Eylül, Konya, Türkiye, 30-36.
  • Kaufmann, B., Christen, P. (2002). Recent extraction techniques for natural products: microwaveassisted extraction and pressurised solvent extraction. Phytochemical analysis, 13, 105–113.
  • Kaya, D., Ergönül, P. G. (2015). Obtaining methods of volatile oils. GIDA-Journal of Food, 40 (5), 303-310.
  • Kongkiatpaiboon, S., Gritsanapan, W. (2013). Optimized extraction for high yield of insecticidal didehydrostemofoline alkaloid in Stemona collinsiae root extracts. Industrial Crops and Products, 41, 371-374.
  • Kumar, P., Yadav, D., Kumar, P., Panesar, P. S., Bunkar, D. S., Mishra, D., Chopra, H. K. (2016). Comparative study on conventional, ultrasonication and microwave assisted extraction of γ-oryzanol from rice bran. Journal of Food Science Technology, 53, 2047-2053.
  • Kumar, A., Nirmal, P., Kumar, M., Jose, A., Tomer, V., Oz, E., Proestos, C., Zeng, M., Elobeid Oz, F. (2023). Major Phytochemicals: Recent Advances in Health Benefits and Extraction Method. Molecules, 28, 887.
  • Lakka, A., Bozinou, E., Makris, D. P., Lalas, S. L. (2021). Evaluation of Pulsed Electric Field Polyphenol Extraction from Vitis vinifera, Sideritis scardica and Crocus sativus. Chemengineering, 5, 25.
  • Liu, T., Sui, X., Li, L., Zhang, J., Liang, X., Li, W., Zhang, H. (2016). Application of ionic liquids based enzyme-assisted extraction of chlorogenic acid from Eucommia ulmoides leaves. Analytica Chimica Acta, 903, 91-99.
  • Liu, Z., Esveld, E., Vincken, J., Bruins, M. E. (2019). Pulsed Electric Field as an Alternative Pre-treatment for Drying to Enhance Polyphenol Extraction from Fresh Tea Leaves. Food and Bioprocess Technology, 12, 183-192.
  • Machado, C. A., Oliveira, F. O., de Andrade, M. A., Saraiva Hodel, K. V., Lepikson, H., Souza Machado, B. A. (2022). Steam distillation for essential oil extraction: An evaluation of technological advances based on ana analysis of patent documents. Sustainability, 14, 7119.
  • Maier, T., Schieber, A., Kammerer, D. R., Carle, R. (2009). Residues of grape (Vitis vinifera L.) seed oil production as a valuable source of phenolic antioxidants. Food Chem, 112, 551-559.
  • Majekodunmi, S. O. (2015). Review of extraction of medicinal plants for pharmaceutical research. Merit research journal of medicine and medical sciences, 3(11), 521-527.
  • Memarzadeh, S. M., Gholami, A., Pirbalouti, A. G., Masoum, S. (2020). Bakhtiari savory (Satureja bachtiarica Bunge.) essential oil and its chemical profile, antioxidant activities, and leaf micromorphology under green and conventional extraction techniques. Industrial Crops & Products, 154, 112719.
  • Mohan, K., Ganesan, A. R., Ezhilarasi, P. N., Kondamareddy, K. K., Rajan, D. K., Sathishkumar, P., Rajarajeswaran, J., Conterno, L. (2022). Green and eco-friendly approaches for the extraction of chitin and chitosan: A review. Arbohydrate Polymers, 287, 119349.
  • Mousavi, S. A., Nateghi, L., Dakheli, M. J., Ramezan, Y., Piravi-Vanak, Z. (2022). Maceration and ultrasound-assisted methods used for Extraction of phenolic compounds and Antioxidant activity from Ferulago angulata. Journal of Food Processing and Preservation, 46 (3), 16356.
  • Mustafa, A., Turner, C. (2011). Pressurized liquid extraction as a green approach in food and herbal plants extraction: A review. Analytica Chimica Acta, 703 (1), 8.
  • Olaiya, N. G., Oyekanmi, A. A., Hanafiah, M. M., Olugbade, T. O., Adeyeri, M. K., Olaiya, F. G. (2022). Enzyme-assisted extraction of nanocellulose from textile waste: A review on production technique and applications. Bioresource Technology Reports, 19, 101183.
  • Oluwaseun, R. A., Nour, H. A., Chinonso, I. U. (2018). Soxhlet extraction of phenolic compounds from Vernonia cinerea leaves and its antioxidant activity. Journal of Applied Research on Medicinal and Aromatic Plants, 11, 12-17.
  • Oprescu, E. E., Enascuta, C. E., Radu, E., Ciltea-Udrescu, M., Lavric, V. (2022). Does the ultrasonic field improve the Extraction productivity compared to classical methods – Maceration and reflux distillation? Chemical Engineering and Processing – Process Intensification, 179, 109082.
  • Özer, Z., Kılıç, T., Çarıkçı, S., Yılmaz, H. (2018). Investigation of phenolic compounds and antioxidant activity of Teucrium polium L. decoction and infusion. J. BAUN Inst. Sci. Tchnol., 20(1), 212-218.
  • Öztekin, S., Soysal, Y. (1998). Tıbbi ve Aromatik Bitkilerde Ekstraksiyon Yöntemi. Tarımsal Mekanizasyon 18. Ulusal Kongresi, Tekirdağ, 731-745.
  • Pawliszyn, J. (2003). Sample preparation: ouo vadis? Analytical Chemistry, 75 (11), 2543.
  • Radosevic, K., Bubalo, M. C., Srcek, V. G., Grgas, D., Dragicevic, T. L., Redovnikavic, I. R. (2015). Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents. Ecotoxicology and Environmental Safety, 112, 46-53.
  • Radwan, M. N., Morad, M. M., Ali, M. M., Wasfy, K. I. (2020). Extraction of peppermint volatile oil using a simple constructed steam distillation system. Plant Archives, 20, 1487-1491.
  • Rasul, M. G. (2018). Extraction, Isolation and Characterization of Natural Products from medicinal Plants. International Journal of Basic Sciences and Applied Computing (ıjbsac), 2, 6.
  • Richter, B. E., Jones, B. A., Ezzell, J. L., Porter, N. L., Avdalovic, N., Pohl, C. (1996). Accelerated solvent extraction: A technique for sample preparation. Analytical Chemistry, 68 (6), 1033.
  • Rodrigues, L. G. G., Mazzutti, S., Siddique, I., da Silva, M., Vitali, L., Ferreira, S. R. S. (2020). Subcritical water extraction and microwave-assisted extraction applied for the recovery of bioactive components from Chaya (Cnidoscolus aconitifolius Mill.) The Journal of Supercritical Fluids, 165, 104976.
  • Saim, N., Dean, J. R., Abdullah, M. P., Zakaria, Z. (1997). Extraction of polycyclic aromatic hydrocarbons from contaminated soil using soxhlet extraction, pressurised and atmospheric microwave-assisted extraction, supercritical fluid extraction and accelerated solvent extraction. Journal of Chromatography A, 791 (2), 361.
  • Samaram, S., Mirhosseini, H., Tan, C. P., Ghazali, H. M. (2013). Ultrasound-assisted extraction and solvent extraction of papaya seed oil: Crystallization and thermal behavior, saturation degree, color and oxidative stability. Ind Crops Prod, 52, 702-708.
  • Sasıkala, M., Sundaraganapathy, R. (2017). Preliminary Phytochemical Evaluation of Hydroalcoholic Extract of Ipomoea Aquatica Forssk. From Alıyar Riverinein South India. International Journal of Pharma and Bio Sciences, 8(3), 356-365.
  • Song, Y., Han, A., Park, S., Cho, C., Rhee, Y., Hong, H. (2020). Effect of enzyme-assisted extraction on the physicochemical properties and bioactive potential of lotus leaf polysaccharides. International Journal of Biological Macromolecules, 153, 169-179.
  • Spigno, G., De Faveri, D. (2009). Microwave-assisted extraction of tea phenols: a phenomenological study. Journal of Food Engineering, 93, 210-217.
  • Strati, I. F., Gogou, E., Oreopoulou, V. (2015). Enzyme and high pressure assisted extraction of carotenoids from tomato waste. Food and Bioproducts Processing, 94, 668-674.
  • Şahin, Ö. (2019). Determination of components of extracted from different parts of melocan (smilax excelsa L.) plant by microwave and ultrasonic assisted extraction. Hacettepe Üniversitesi, Gıda Mühendisliği Anabilim Dalı Yüksek Lisans Tezi, 125.
  • Tadeo, J. L., Sanchez-Brunete, C., Albero, B., Garcia-Valcarcel, A. I. (2010). Application of ultrasound- assisted extraction to the determination of contaminants in food and soil samples. Journal of Chromatography A, 1217 (16), 2415.
  • Tiring, G., Satar, S., Özkaya, O. (2021). Sekonder Metabolitler. Journal of Agricultural Faculty of Bursa Uludağ University, 35(1), 203-215.
  • Tokkan, D., Kuşlu, S., Çalban, T., Çolak, S. (2012). Anod Çamurundaki Gümüşün Amonyum Tiyosülfat Çözeltilerinde Mikrodalga Enerjisi ile Ekstraksiyonunun Optimizasyonu. Onuncu Ulusal Kimyasal Mühendisliği Kongresi, Koç Üniversitesi, İstanbul, 3-6 Eylül.
  • Vurdu, H., (1989), Pinus nigra Arnold Foliage. Journal of Islamic Academy of Sciences, 2, 106-108.
  • Wen, C., Zhang, J., Zhang, H., Dzah, C. S., Zandile, M., Duan, Y., Ma, H., Luo X. (2018). Advances in ultrasound assisted extraction of bioactive compounds from cash crops. Ultrasonics-Sonochemistry, 48, 538-549.
  • Xavier, V. B., Vargas, R. M. F., Cassel, E., Lucas, A. M., Santos, M. A., Mondin, C. A., Santarem, E. R., Astarita, L. V., Sartor, T. (2011). Mathematical modeling for extraction of essential oil from Baccharis spp. by steam distillation. Ind. Crop. Prod., 33, 599-604.
  • Yılmaz, F. M., Özer, P., Görgüc, A. (2018). Mikrodalga teknolojisinin bitkisel dokulardan makro ve mikro bileşenlerin özütlenmesinde kullanımı. Gıda/The Journal of Food, 43, 765-775.
  • Yusoff, I. M., Taher, Z. M., Rahmat, Z., Chua, L. S. (2022). Areview of ultrasound-assisted Extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins. Food Research International, 157, 111268.
  • Zhang, Q. W., Lin, L. G., Ye, W. C. (2018). Ttechniques for extraction and isolation of natural products: a comprehensive review. Chinese Mmedicine, 13,20.
  • Zhang, W. L., Chen, J. P., Lam, K. Y., Zhan, J. Y., Yao, P., Dong, T. T., Tsim, K. W. (2014). Hydrolysis of Glycosidic Flavonoids during the Preparation of Danggui Buxue Tang: An Outcome of Moderate Boiling of Chinese Herbal Mixture. Evidence-Based Complementary and Alternative Medicine, 608721.
  • Zougagh, M., Valcarcel, M., Rios, A. (2004). Supercritical fluid extraction: a critical review of its analytical usefulness. Trac-Trends in Analytical Chemistry, 23 (5), 399.
There are 101 citations in total.

Details

Primary Language English
Subjects Forest Industry Engineering
Journal Section Review Articles and Editorials
Authors

Didem Verep 0000-0002-1013-9212

Saim Ateş 0000-0003-0589-1773

Eyyüp Karaoğul 0000-0001-8162-6838

Publication Date December 15, 2023
Published in Issue Year 2023 Volume: 25 Issue: 3

Cite

APA Verep, D., Ateş, S., & Karaoğul, E. (2023). A Review of Extraction Methods for Obtaining Bioactive Compounds in Plant-Based Raw Materials. Bartın Orman Fakültesi Dergisi, 25(3), 492-513. https://doi.org/10.24011/barofd.1303285


Bartin Orman Fakultesi Dergisi Editorship,

Bartin University, Faculty of Forestry, Dean Floor No:106, Agdaci District, 74100 Bartin-Turkey.

Fax: +90 (378) 223 5077, Fax: +90 (378) 223 5062,

E-mail: bofdergi@gmail.com